Thursday, November 13, 2014

Article Number: 9946

Newsgroups: alt.psychoactives

Subject: Calea zacatechichi


From: (Mark Thompson)

Date: 2 May 93 08:13:47 GMT

>Someone asked about Calea zacatechichi...

Beside Willam Bodens book "Narcotic Plants" and Richard Evan

Schultes/Albert Hofmann's book "Plants of the Gods", a good source of info

about psychoactive Mexican plants is the article:

"Ethnopharmacology and Taxonomy of Mexican Psychodysleptic Plants"

by Jose Luis Diaz, MD published in the Jan-Jun 1979 issue of

"Journal of Psychedelic Drugs"

Diaz lists Salvia divinorum, Calea zacatechichi and Cannabis sativa

as "cognodysleptics", and Calea zacatechichi is mentioned as being smoked

and taken as a tea by the Chontal Indians in Oaxaca for divination and

oneiromancy (dream induction).

"Its actions during wakefulness were tested in five subjects after

several inhalations and the administration of an infusion.

With high doses, effects included: sensations of well-being

and light-headedness, difficulty in bringing events to mind,

somnolence, and an intensification of visual imagery, but only

with the eyes closed."

It isn't clear from the paper whether the psychoactive substance(s) in

the plant have been conclusively identified:

"A germacranolid called caleicine, the p-hydroxycinnamide ester of

junenol, was isolated from a sample of C. zacatechichi taken from

the state of Veracruz."

"Other substances with the basic structure of caleicine have been

isolated from the active, as well as the inactive plants provided

by the Chontal curandero; they are now being screened for the

presence of psychoactive compounds. Independently Bohlmann and

Zdero(1977) have reported two new germacranolids in C. zacatechichi.

It should be mentioned that these molecules are terpenes as are the

cannabinols in marijuana."

Diaz also mentions that there appear to be two varieties (possibly

separate species) of this plant. One is psychoactive and the other

apparently is not.


Hope that's useful to someone.

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